Haunted houses, frat-house feuds and festival-prize dramas sit side by side here, because Byrne has never stayed in one lane for long. Some picks are blockbusters, others barely left Australia.
1AdamMax Mayer's 2009 romantic drama about a man with Asperger syndrome, played by Hugh Dancy, and his neighbor Beth, played by Byrne.1000pts
2NeighborsNicholas Stoller's 2014 comedy with Byrne and Seth Rogen as new parents feuding with a fraternity led by Zac Efron.999pts
3This Is Where I Leave YouShawn Levy's 2014 family comedy-drama starring Jason Bateman and Tina Fey, with Byrne as Penny Moore.900pts
4BridesmaidsPaul Feig's 2011 comedy in which Byrne plays Helen, the polished rival of Kristen Wiig's maid of honor.900pts
5KnowingAlex Proyas's 2009 science-fiction thriller starring Nicolas Cage, with Byrne as Diana Wayland, the daughter of a woman who predicted disasters.877pts
6The Goddess of 1967Clara Law's 2000 Australian road movie that won Byrne the Volpi Cup for Best Actress at the Venice Film Festival.771pts
7If I Had Legs I'd Kick YouMary Bronstein's 2025 A24 drama with Byrne as an overwhelmed mother and therapist, a role that won her the Berlinale Silver Bear for Best Leading Performance.771pts
8Get Him to the GreekNicholas Stoller's 2010 comedy with Russell Brand and Jonah Hill, in which Byrne plays the pop star Jackie Q.692pts
928 Weeks LaterJuan Carlos Fresnadillo's 2007 sequel to 28 Days Later, with Byrne as US Army medical officer Scarlet in a reinfected London.600pts
10Insidious: Chapter 2The 2013 James Wan sequel in which Byrne returns as Renai Lambert, whose family is still haunted after the events of the first film.600pts
11Two HandsGregor Jordan's 1999 Australian crime comedy starring Heath Ledger, with Byrne as Alex in one of her first film roles.600pts
12SunshineDanny Boyle's 2007 science-fiction film about a crew sent to reignite the dying Sun, with Byrne as the pilot Cassie.491pts
13Instant FamilySean Anders's 2018 comedy-drama with Byrne and Mark Wahlberg as a couple who foster three siblings.360pts
14Peter RabbitWill Gluck's 2018 live-action and animated adaptation of Beatrix Potter's stories, with Byrne as the painter Bea.360pts
15InsidiousJames Wan's 2010 supernatural horror film with Byrne and Patrick Wilson as parents whose son falls into a mysterious coma.360pts
16X-Men: First ClassMatthew Vaughn's 2011 superhero prequel set in 1962, with Byrne as CIA agent Moira MacTaggert.360pts
17Neighbors 2: Sorority RisingThe 2016 sequel in which Byrne and Seth Rogen's couple face a new sorority moving in next door, led by Chloe Grace Moretz.360pts
18SpyPaul Feig's 2015 spy comedy starring Melissa McCarthy, with Byrne as the haughty arms dealer Rayna Boyanov.0pts
19TroyWolfgang Petersen's 2004 epic of the Trojan War starring Brad Pitt, with Byrne as the Trojan priestess Briseis.0pts
20Marie AntoinetteSofia Coppola's 2006 period drama starring Kirsten Dunst, with Byrne as the queen's confidante the Duchesse de Polignac.0pts
21Juliet, NakedJesse Peretz's 2018 adaptation of the Nick Hornby novel, with Byrne as Annie opposite Ethan Hawke and Chris O'Dowd.0pts
22AnnieWill Gluck's 2014 modern remake of the musical starring Quvenzhane Wallis and Jamie Foxx, with Byrne as Grace Farrell.0pts






















