What is the best anime about siblings?

Brothers chasing a cure, sisters meeting forest spirits, twins raised in show business. A few of these will wreck you.

1. 1
   Grave of the Fireflies

   Isao Takahata's 1988 Studio Ghibli film about Seita and his little sister Setsuko trying to survive in Japan at the end of World War II.
   1000pts
2. 2
   Fullmetal Alchemist: Brotherhood

   Bones' 64-episode 2009–2010 series that follows Hiromu Arakawa's manga about Edward and Alphonse Elric to its ending.
   942pts
3. 3
   Code Geass

   Sunrise's 2006–2008 series about Lelouch, an exiled prince who leads a rebellion against an empire partly to build a safe world for his sister Nunnally.
   668pts
4. 4
   No Game No Life

   Madhouse's 2014 series about Sora and Shiro, step-siblings and unbeatable gamers who are pulled into a world where every dispute is settled by games.
   565pts
5. 5
   Demon Slayer

   Ufotable's adaptation of Koyoharu Gotouge's manga, begun in 2019, in which Tanjiro Kamado hunts demons while searching for a cure for his sister Nezuko.
   439pts
6. 6
   Fullmetal Alchemist (2003)

   Bones' 51-episode 2003–2004 series about Edward and Alphonse Elric, brothers who lose a leg and an entire body trying to bring their mother back with alchemy.
   439pts
7. 7
   Wolf Children

   Mamoru Hosoda's 2012 film about Yuki and Ame, half-wolf siblings raised by their mother, who grow up to choose different lives.
   439pts
8. 8
   My Neighbor Totoro

   Hayao Miyazaki's 1988 Studio Ghibli film about sisters Satsuki and Mei, who meet forest spirits after moving to the countryside.
   439pts
9. 9
   Naruto Shippuden

   Pierrot's 2007–2017 series, the second part of Masashi Kishimoto's Naruto, in which Sasuke's hunt for his brother Itachi drives much of the story.
   0pts
10. 10
    Mob Psycho 100

    Bones' 2016–2022 adaptation of ONE's manga about a psychic middle-schooler, Mob, and his younger brother Ritsu.
    0pts
11. 11
    Oshi no Ko

    Doga Kobo's adaptation of Aka Akasaka and Mengo Yokoyari's manga, begun in 2023, about twins Aqua and Ruby growing up in the entertainment industry.
    0pts

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