The 24 Best Spider-Man Villains of All Time

From tragic scientists gone wrong to cold-blooded masterminds bent on wrecking Peter Parker's life, this rogues' gallery spans every era of the wall-crawler's world. Which villain reigns supreme?

1

Green Goblin

Norman Osborn, Spider-Man's arch-nemesis and a brilliant industrialist turned murderous glider-riding madman.

1000pts

2

Venom

Eddie Brock bonded with an alien symbiote that once rejected Peter Parker, becoming a monstrous mirror-image enemy.

912pts

3

Kraven the Hunter

Sergei Kravinoff, a big-game hunter obsessed with proving himself by killing Spider-Man, the ultimate prey.

750pts

4

Alistair Smythe

The vengeful son of the original Spider-Slayer creator, who builds increasingly deadly robotic hunters to destroy Spider-Man.

700pts

5

Rhino

Aleksei Sytsevich, a hulking brute encased in an armored suit granting super-strength and near invulnerability.

642pts

6

Shocker

Herman Schultz, a career criminal whose vibro-shock gauntlets let him blast enemies and shake off punishment.

577pts

7

Silvermane

Silvio Manfredi, an aging Maggia crime boss obsessed with immortality who has used cybernetics to extend his criminal reign.

576pts

8

Mister Negative

Martin Li, a philanthropist with a corrupted alter ego who can invert life force to devastating effect.

500pts

9

Carnage

Serial killer Cletus Kasady merged with a symbiote offspring of Venom to become an even more sadistic threat.

500pts

10

Vulture

Adrian Toomes, an elderly engineer whose flight harness makes him one of Spider-Man's oldest and most persistent foes.

409pts

11

Lizard

Dr. Curt Connors, a scientist whose reptile-regeneration formula transforms him into a savage, reptilian alter ego.

409pts

12

Doctor Octopus

Otto Octavius, a nuclear physicist fused with four mechanical arms who became one of Spider-Man's most cunning foes.

409pts

13

Mysterio

Quentin Beck, a former special-effects man who uses illusions and trickery to torment Spider-Man psychologically.

409pts

14

Morbius

Michael Morbius, a biochemist whose failed cure for a blood disease turned him into a pseudo-vampire with superhuman powers.

409pts

15

Molten Man

Mark Raxton, a lab assistant fused with a liquid metal alloy that makes his molten body dangerous to the touch.

409pts

16

Scorpion

Mac Gargan, a private investigator turned mutated, tail-wielding predator engineered specifically to destroy Spider-Man.

409pts

17

Sandman

William Baker, a career criminal transformed into a shape-shifting sand-bodied villain nearly impervious to physical harm.

300pts

18

Chameleon

Dmitri Smerdyakov, a master of disguise and Spider-Man's very first supervillain, able to impersonate anyone perfectly.

300pts

19

Puma

Thomas Fireheart, a shapeshifting mercenary with enhanced feline strength, speed, and senses who has both fought and aided Spider-Man.

300pts

20

Electro

Maxwell Dillon, an electrical lineman turned living generator who can control and discharge massive voltages.

300pts

21

Hobgoblin

Roderick Kingsley, a schemer who took up Green Goblin's abandoned gear to become a cunning, calculating copycat villain.

300pts

22

Kingpin

Wilson Fisk, New York's towering crime lord whose vast criminal empire has clashed with Spider-Man for decades.

167pts

23

Jackal

Miles Warren, a geneticist obsessed with cloning who orchestrated the infamous Clone Saga against Spider-Man.

167pts

24

Tombstone

Lonnie Lincoln, an albino mob enforcer with stone-hard invulnerable skin and brutal physical strength.

167pts